Bacteria Diseases
The neglected bacterial diseases comprise serious and often lethal conditions caused by a large number of bacteria, ranging from the mycobacteria family (causing leprosy and Buruli ulcer) to Chlamydia (causing trachoma) and gastrointestinal bacteria such as enterotoxigenic E. coli (ETEC) and Shigella (both causing infantile diarrhoea).
| PRIORITY DISEASES |
Main Infectious Agent |
| KEY RESEARCH GAPS |
| Discovery and Development |
Disease Control and Implementation Research |
|
| Buruli ulcer |
Mycobacterium ulcerans |
| Basic immunology for future vaccine development, drug and diagnostic development |
Epidemiology, diagnostics |
|
| Leprosy |
Mycobacterium leprae |
| Basic immunology for future vaccine development, drug and diagnostic development | Diagnostics |
|
| Trachoma |
Chlamydia trachomatis |
| Vaccine development, immunopathogenesis, predictive animal models |
Diagnostics |
|
| Infantile diarrhoea |
Enterotoxigenic Escherichia coli (ETEC)
Shigella genus |
| Vaccines, drug resistance |
Diagnostics (able to differentiate between gut infections), Improved control |
|
