MetaHIT

The four-year project ‘Metagenomics of the Human Intestinal Tract’ will focus on the microorganisms of the gut, which play an important role in human health and well-being. The project will open avenues to modulate human gut microbiota, which may lead to optimising the health and well-being of any individual.

The project involves 15 partners from the following 8 countries:
France, Denmark, Germany, Spain, Italy, the Netherlands, United Kingdom and China.
EC contribution: €11.4 million
Website

SYBILLA

The five-year project ‘Systems Biology of T-cell Activation in Health and Disease’ aims to understand, at the systems level, how T-cells discriminate ‘foreign’ from ‘auto’ antigens. T-cell activation is a complex process relying on multiple layers of tightly controlled intracellular signalling modules that form an intricate network. Defects in this network can cause severe and chronic disorders such as autoimmune diseases.

The project involves 17 partners from the following 9 countries:
United Kingdom, Germany, Spain, Austria, Switzerland, France, Italy, Finland, Czech Republic, USA and India.
EC contribution: €11.1 million
http://www.sybilla-t-cell.de/

BIOSHARE-EU

This 5-year project aims to harmonise and standardise the collection, storage, and management of data and biosamples across large-scale biobanking studies in Europe and Canada. The tools to be delivered will enable effective pooling of data and key measures of life-style, social circumstances and environment, as well as critical sub-components of the phenotypes associated with common diseases. Very large sample sizes are needed to investigate current questions in multifactorial diseases, notably on gene-environment interactions.

The project brings together 16 participants from the following 9 countries: The Netherlands, United Kingdom, Norway, Finland, Germany, Sweden, France, Austria and Canada.
EU-contribution: 11.998.152 EUR
http://www.bioshare.eu/

ENGAGE

This 5-year project aims at translating the wealth of data emerging from large-scale research efforts in molecular epidemiology into information of direct relevance to future advances in clinical medicine. The goal is to identify large numbers of novel susceptibility genes that influence metabolic, behavioural and cardiovascular traits, and to study the interactions between genes and life style factors.

The project brings together 25 participants from the following 12 countries: Finland, United Kingdom, Germany, the Netherlands, Sweden, Norway, Estonia, Iceland, Spain, and Latvia, Canada and Australia.
EU contribution 12.000.000 EUR
http://www.euengage.org